Article
Tumor suppress genes screening analysis on 4q in sporadic colorectal carcinoma.
World journal of gastroenterology - 28 Sept 2008
Jiang Li-Xin, Xu Jie, Wang Zhao-Wen, Li Da-Peng, Peng Zhi-Hai, Gao Jian-Jun, He Lin, Zheng Hai-Tao
Abstract excerpt
AIM: To search candidate tumor suppressor genes (TSGs) on chromosome 4q through detecting high loss of heterozygosity (LOH) regions in sporadic colorectal carcinoma in Chinese patients. METHODS: Thirteen fluorescent labeled polymorphic microsatellite markers were analyzed in 83 cases of colorectal carcinoma and matched normal tissue DNA by polymerase chain reaction (PCR). PCR products were electrophoresed on an...
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