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Identification of a new target region by loss of heterozygosity at 5p15.33 in sporadic gastric carcinomas: genotype and phenotype related.

Cancer letters - 28 Jun 2005

Lu Yun, Yu Yingyan, Zhu Zhenggang, Xu Heng, Ji Jun, Bu Lei, Liu Bingya, Jiang Haisong, Lin Yanzhen, Kong Xiangyin, Hu Landian

Abstract excerpt

Chromosome 5p, especially 5p15, involves in several cancers. To investigate its role in gastric cancer, we analyzed 46 intestinal-type and 34 diffuse-type gastric cancers by Loss of heterozygosity (LOH). We found a high frequent LOH at 5p15.33, and identified a minimal 2.7 cM candidate region of tumor suppressor gene, encompassing four loci (D5S417, D5S2849, D5S1492 and D5S2088). In total 80 cases, the highest...

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PMID: 15914283
DOI: 10.1016/j.canlet.2004.11.057

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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