Article
Association between PTEN IVS4 polymorphism and development of colorectal cancer in a Turkish population.
Expert opinion on therapeutic targets - 1 Jan 2013
Canbay Emel, Kahraman Ozlem T, Bugra Dursun, Caykara Burcu, Seyhan Mehmet Fatih, Bulut Turker, Yamaner Sumer, Ozturk Oguz
Abstract excerpt
BACKGROUND: Phosphatase and tensin homolog (PTEN) is one of the most frequently mutated suppressor genes in human cancers. However, there are no data about the role of PTEN IVS4 polymorphism in development of colorectal cancer (CRC). The authors aimed to determine the role of PTEN IVS4 variants in the etiology of CRC. PATIENTS AND METHODS: A hospital-based case-control study was conducted in 203 patients with CRC...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
