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Article

Analysis of loss of heterozygosity on chromosome 4q in hepatocellular carcinoma using high-throughput SNP array.

Oncology reports - 1 Feb 2010

Zhang Huakun, Ma Haiqing, Wang Qijing, Chen Minshan, Weng Desheng, Wang Hui, Zhou Jun, Li Yongqiang, Sun Jiancong, Chen Yibing, Liang Xiaoting, Zhao Jingjing, Pan Ke, Wang Huiyun, Xia Jianchuan

Abstract excerpt

To identify tumour suppressor genes (TSGs) associated with hepatocellular carcinoma (HCC) on chromosome 4q using a high-throughput single nucleotide polymorphism (SNP) array, we first scanned for loss of heterozygosity (LOH) of 40 SNPs on chromosome 4q and discovered 2 hot regions: 4q24-26 and 4q34.3-35. We then further scanned for LOH of 338 SNPs in genes around 4q34.3-35 and discovered 3 genes with the most...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 20043106

Genes

ING2
NEIL3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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