[Allelic analysis on chromosome 5 in sporadic colorectal cancer patients].

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Article

[Allelic analysis on chromosome 5 in sporadic colorectal cancer patients].

Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 Sept 2002

Zhang Fang, Zhou Chongzhi, Ling Yun, Qiu Guoqiang, Bai Shaochun, Liu Wanqing, He Lin, Peng Zhihai

Abstract excerpt

OBJECTIVE: To evaluate and map the putative tumor suppressor loci on chromosome 5 involved in tumor progress or metastasis. METHODS: Chromosome 5 of 83 patients with sporadic colorectal cancer was systemically screened. Fifteen microsatellite marker primers labeled with 3 different fluorescents were used to amplify the corresponding loci of the genome DNA. The PCR products were electrophoresed on a 377 PRISM...

Topics

Adult
Aged
Aged, 80 and over
Alleles
Chromosome Deletion
Chromosomes, Human, Pair 5
Colorectal Neoplasms
Female
Genes, Tumor Suppressor
Humans
Loss of Heterozygosity
Male
Microsatellite Repeats
Middle Aged

Source

Open in PubMed

Identifiers

PMID: 12485498

Genes

APC
CTNNA1
MCC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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