Article
Refinement of heterozygosity loss on chromosome 5p15 in sporadic colorectal cancer.
World journal of gastroenterology - 1 Aug 2003
Xu Shi-Feng, Peng Zhi-Hai, Li Da-Peng, Qiu Guo-Qiang, Zhang Fang
Abstract excerpt
AIM: To refine the loss of heterozygosity on chromosome 5p15 and to identify the new tumor suppressor gene (s) in colorectal tumorigenesis. METHODS: Sixteen polymorphic microsatellite markers were analyzed on chromosome 5 and another 6 markers were applied on chromosome 5p15 in 83 cases of colorectal and normal DNA by PCR. PCR products were electrophoresed on an ABI 377 DNA sequencer. Genescan 3.1 and Genotype...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
