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Article

Loss of heterozygosity analyzed by single nucleotide polymorphism array in cancer.

World journal of gastroenterology - 21 Nov 2005

Zheng Hai-Tao, Peng Zhi-Hai, Li Sheng, He Lin

Abstract excerpt

Neoplastic progression is generally characterized by the accumulation of multiple genetic alterations including loss of tumor suppression gene function. Loss of heterozygosity (LOH) has been used to identify genomic regions that harbor tumor suppressor genes and to characterize different tumor types, pathological stages and progression. LOH pattern has been detected by allelotyping using restriction fragment...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16425377
DOI: 10.3748/wjg.v11.i43.6740
PMCID: PMC4725022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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