Article
The association between -1304T>G polymorphism in the promoter of MKK4 gene and the risk of sporadic colorectal cancer in southern Chinese population.
International journal of cancer - 15 Oct 2009
Wei Yisheng, Wang Lei, Lan Ping, Zhao Hongjun, Pan Zhizhong, Huang Jun, Lu Jiachun, Wang Jianping
Abstract excerpt
MKK4 (mitogen-activated protein kinase kinase 4, NM_003010.2), which belongs to the mitogen-activated protein kinase pathways, possesses functions in tumorigenesis. We hypothesized the genetic variants in MKK4 gene may alter its functions and thus cancer risk. In current hospital-based case-contr...
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