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Article

Activation-induced cytidine deaminase links between inflammation and the development of colitis-associated colorectal cancers.

Gastroenterology - 1 Sept 2008

Endo Yoko, Marusawa Hiroyuki, Kou Tadayuki, Nakase Hiroshi, Fujii Shigehiko, Fujimori Takahiro, Kinoshita Kazuo, Honjo Tasuku, Chiba Tsutomu

Abstract excerpt

BACKGROUND & AIMS: Activation-induced cytidine deaminase (AID) was originally identified as an inducer of somatic hypermutations in the immunoglobulin gene. We recently revealed that ectopic AID expression serves as a link between the cellular editing machinery and high mutation frequencies, leading to human cancer development. In the current study, we investigated whether AID might contribute to the development...

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PMID: 18691581
DOI: 10.1053/j.gastro.2008.06.091

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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