Article
Expression of activation-induced cytidine deaminase in human hepatocytes during hepatocarcinogenesis.
International journal of cancer - 1 Feb 2007
Kou Tadayuki, Marusawa Hiroyuki, Kinoshita Kazuo, Endo Yoko, Okazaki Il-Mi, Ueda Yoshihide, Kodama Yuzo, Haga Hironori, Ikai Iwao, Chiba Tsutomu
Abstract excerpt
Activation-induced cytidine deaminase (AID) plays a role as a genome mutator in activated B cells, and inappropriate expression of AID has been implicated in the immunopathological phenotype of human B-cell malignancies. Notably, we found that the transgenic mice overexpressing AID developed lung...
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