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Article

Expression of activation-induced cytidine deaminase in human hepatocytes during hepatocarcinogenesis.

International journal of cancer - 1 Feb 2007

Kou Tadayuki, Marusawa Hiroyuki, Kinoshita Kazuo, Endo Yoko, Okazaki Il-Mi, Ueda Yoshihide, Kodama Yuzo, Haga Hironori, Ikai Iwao, Chiba Tsutomu

Abstract excerpt

Activation-induced cytidine deaminase (AID) plays a role as a genome mutator in activated B cells, and inappropriate expression of AID has been implicated in the immunopathological phenotype of human B-cell malignancies. Notably, we found that the transgenic mice overexpressing AID developed lung adenocarcinoma and hepatocellular carcinoma (HCC), suggesting that ectopic expression of AID can lead to tumorigenesis...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17066440
DOI: 10.1002/ijc.22292

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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