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Article

Inflammation-mediated genomic instability: roles of activation-induced cytidine deaminase in carcinogenesis.

Cancer science - 1 Jul 2012

Shimizu Takahiro, Marusawa Hiroyuki, Endo Yoko, Chiba Tsutomu

Abstract excerpt

Chronic inflammation is a strong risk factor for the development of cancer. Many previous studies have demonstrated that a transcriptional factor, nuclear factor (NF)-κB, plays an important role in the association between inflammation and cancer development, particularly tumor promotion and tumor progression. Although it is well recognized that cancer develops via stepwise accumulation of genetic aberrations, the...

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Source

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Identifiers

PMID: 22469133
DOI: 10.1111/j.1349-7006.2012.02293.x
PMCID: PMC7659292

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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