Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Activation-induced cytidine deaminase links bile duct inflammation to human cholangiocarcinoma.

Hepatology (Baltimore, Md.) - 1 Mar 2008

Komori Junji, Marusawa Hiroyuki, Machimoto Takafumi, Endo Yoko, Kinoshita Kazuo, Kou Tadayuki, Haga Hironori, Ikai Iwao, Uemoto Shinji, Chiba Tsutomu

Abstract excerpt

UNLABELLED: Chronic inflammation plays a critical role in oncogenesis in various human organs. Epidemiological studies have demonstrated that patients with primary sclerosing cholangitis have a predisposition to develop cholangiocarcinoma (CC). However, the molecular mechanisms that account for t...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to AICDA (Activation-Induced Cytidine Deaminase)
Share to Bile Duct Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Bile Ducts, Intrahepatic

Share to Cholangiocarcinoma

Share to Cyclin-Dependent Kinase Inhibitor p16

Share to Cytidine Deaminase

Share to Mutagenesis

Share to Proto-Oncogene Proteins c-myc

Source

Identifiers

PMID: 18306229
DOI: 10.1002/hep.22125

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18306229-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Activation-induced cytidine deaminase links bile duct inflammation to human cholangiocarcinoma.PMID 18306229Read ↗

Activation-induced cytidine deaminase links between inflammation and the development of colitis-associated colorectal cancers.Semantic proximity Read ↗

Expression of activation-induced cytidine deaminase in human hepatocytes during hepatocarcinogenesis.Semantic proximity Read ↗

Inflammation-mediated genomic instability: roles of activation-induced cytidine deaminase in carcinogenesis.Semantic proximity Read ↗

Hepatic inflammation facilitates transcription-associated mutagenesis via AID activity and enhances liver tumorigenesis.Semantic proximity Read ↗

A novel mechanism for inflammation-associated carcinogenesis; an important role of activation-induced cytidine deaminase (AID) in mutation induction.Semantic proximity Read ↗

Activation-induced cytidine deaminase mRNA expression in oral squamous cell carcinoma-derived cell lines is upregulated by inflammatory cytokines.Semantic proximity Read ↗

Expression of activation-induced cytidine deaminase in human hepatocytes via NF-κB signalingSemantic proximity Read ↗

Cholangiocarcinomas associated with long-term inflammation express the activation-induced cytidine deaminase and germinal center-associated nuclear protein involved in immunoglobulin V-region diversification.Semantic proximity Read ↗

Molecular mechanism of cholangiocarcinoma carcinogenesis.Semantic proximity Read ↗

Human cytidine deaminases facilitate hepatitis B virus evolution and link inflammation and hepatocellular carcinoma.Semantic proximity Read ↗

Involvement of activation-induced cytidine deaminase in skin cancer development.Semantic proximity Read ↗

Interleukin-1 and tumor necrosis factor-α trigger restriction of hepatitis B virus infection via a cytidine deaminase activation-induced cytidine deaminase (AID).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.