Article
Colonic carcinogenesis in IBD: molecular events.
Annali italiani di chirurgia - 1 Jan 2000
Pozza Anna, Scarpa Marco, Ruffolo Cesare, Polese Lino, Erroi Francesca, Bridda Alessio, Norberto Lorenzo, Frego Mauro
Abstract excerpt
Patients with ulcerative colitis (UC) and Crohn's disease (CD) are at increased risk of developing intestinal cancers via mechanisms that remain incompletely understood. Several evidences suggest a causal link between chronic inflammation and the development of cancer in the gastrointestinal tract. In fact, patients with UC are exposed to repeated episodes of inflammation that predispose to various tumorigenic...
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