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Article

Mitochondrial nucleoids maintain genetic autonomy but allow for functional complementation.

The Journal of cell biology - 30 Jun 2008

Gilkerson Robert W, Schon Eric A, Hernandez Evelyn, Davidson Mercy M

Abstract excerpt

Mitochondrial DNA (mtDNA) is packaged into DNA-protein assemblies called nucleoids, but the mode of mtDNA propagation via the nucleoid remains controversial. Two mechanisms have been proposed: nucleoids may consistently maintain their mtDNA content faithfully, or nucleoids may exchange mtDNAs dynamically. To test these models directly, two cell lines were fused, each homoplasmic for a partially deleted mtDNA in...

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Identifiers

PMID: 18573913
DOI: 10.1083/jcb.200712101
PMCID: PMC2442202

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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