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Article

Integrity of the yeast mitochondrial genome, but not its distribution and inheritance, relies on mitochondrial fission and fusion.

Proceedings of the National Academy of Sciences of the United States of America - 3 Mar 2015

Osman Christof, Noriega Thomas R, Okreglak Voytek, Fung Jennifer C, Walter Peter

Abstract excerpt

Mitochondrial DNA (mtDNA) is essential for mitochondrial and cellular function. In Saccharomyces cerevisiae, mtDNA is organized in nucleoprotein structures termed nucleoids, which are distributed throughout the mitochondrial network and are faithfully inherited during the cell cycle. How the cell distributes and inherits mtDNA is incompletely understood although an involvement of mitochondrial fission and fusion...

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Identifiers

PMID: 25730886
DOI: 10.1073/pnas.1501737112
PMCID: PMC4352819

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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