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Article

Mitochondrial functional complementation in mitochondrial DNA-based diseases.

The international journal of biochemistry & cell biology - 1 Oct 2009

Nakada Kazuto, Sato Akitsugu, Hayashi Jun-ichi

Abstract excerpt

Mitochondria exist in networks that are continuously remodeled through fusion and fission. Why do individual mitochondria in living cells fuse and divide continuously? Protein machinery and molecular mechanism for the dynamic nature of mitochondria have been almost clarified. However, the biological significance of the mitochondrial fusion and fission events has been poorly understood, although there is a...

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PMID: 19464386
DOI: 10.1016/j.biocel.2009.05.010

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