Article
Effects of Fcj1-Mos1 and mitochondrial division on aggregation of mitochondrial DNA nucleoids and organelle morphology.
Molecular biology of the cell - 1 Jun 2013
Itoh Kie, Tamura Yasushi, Iijima Miho, Sesaki Hiromi
Abstract excerpt
Mitochondrial DNA (mtDNA) is packaged into DNA-protein complexes called nucleoids, which are distributed as many small foci in mitochondria. Nucleoids are crucial for the biogenesis and function of mtDNA. Here, using a yeast genetic screen for components that control nucleoid distribution and size, we identify Fcj1 and Mos1, two evolutionarily conserved mitochondrial proteins that maintain the connection between...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
