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Article

Organization and dynamics of human mitochondrial DNA.

Journal of cell science - 1 Jun 2004

Legros Frédéric, Malka Florence, Frachon Paule, Lombès Anne, Rojo Manuel

Abstract excerpt

Heteroplasmic mutations of mitochondrial DNA (mtDNA) are an important source of human diseases. The mechanisms governing transmission, segregation and complementation of heteroplasmic mtDNA-mutations are unknown but depend on the nature and dynamics of the mitochondrial compartment as well as on the intramitochondrial organization and mobility of mtDNA. We show that mtDNA of human primary and immortal cells is...

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PMID: 15138283
DOI: 10.1242/jcs.01134

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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