Article

When mitochondria fall apart: Unbalanced mitochondrial segregation triggers loss of mtDNA in the absence of mitochondrial fusion

2025-05-13

Abstract excerpt

Mitochondrial biogenesis and inheritance must be carefully regulated alongside cell division to ensure proper mitochondrial function and cell survival. The dynamics of the mitochondrial network, including fusion and fission, play a crucial role in mitochondrial inheritance by facilitating the distribution and quality control of mitochondria. In budding yeast, simultaneous inhibition of both fusion and fission lead...

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Literature Corpus work: cf282bfe-ce3e-51eb-b8a6-795d0c9d71fb
DOI: 10.1101/2025.05.13.653688

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