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Article

Determining prognosis of clinically localized prostate cancer by immunohistochemical detection of mutant p53.

Urology - 1 Mar 1996

Stricker H J, Jay J K, Linden M D, Tamboli P, Amin M B

Abstract excerpt

OBJECTIVES: Mutations of the p53 tumor suppressor gene can result in unregulated cellular growth and have been implicated in numerous malignancies. The objective of this study was to determine whether the detection of mutant p53 by immunohistochemical staining is predictive of progression in clin...

Topics

Adenocarcinoma
Aged
Follow-Up Studies
Genes, p53
Humans
Immunohistochemistry
Logistic Models
Male
Middle Aged
Multivariate Analysis
Mutation
Predictive Value of Tests
Prognosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Prostatic Neoplasms

Retrospective Studies

Tumor Suppressor Protein p53

Source

Identifiers

PMID: 8633403
DOI: 10.1016/S0090-4295(99)80454-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8633403-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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