Article
Determining prognosis of clinically localized prostate cancer by immunohistochemical detection of mutant p53.
Urology - 1 Mar 1996
Stricker H J, Jay J K, Linden M D, Tamboli P, Amin M B
Abstract excerpt
OBJECTIVES: Mutations of the p53 tumor suppressor gene can result in unregulated cellular growth and have been implicated in numerous malignancies. The objective of this study was to determine whether the detection of mutant p53 by immunohistochemical staining is predictive of progression in clinically localized adenocarcinoma of the prostate. METHODS: Immunohistochemical staining for mutant p53 was performed on...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
