Article
Frequency and characterization of p53 mutations in clinically localized prostate cancer.
Urology - 1 Mar 1995
Hall M C, Navone N M, Troncoso P, Pollack A, Zagars G K, von Eschenbach A C, Conti C J, Chung L W
Abstract excerpt
OBJECTIVES: To determine the frequency of abnormal p53 expression and to characterize confirmed p53 mutations in tumors from patients with clinically localized adenocarcinoma of the prostate. METHODS: p53 protein nuclear accumulation was determined immunohistochemically in the initial diagnostic tumor specimens from 37 patients with clinically localized prostate carcinoma. Two primary antibodies were used on all...
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