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Article

Frequency and characterization of p53 mutations in clinically localized prostate cancer.

Urology - 1 Mar 1995

Hall M C, Navone N M, Troncoso P, Pollack A, Zagars G K, von Eschenbach A C, Conti C J, Chung L W

Abstract excerpt

OBJECTIVES: To determine the frequency of abnormal p53 expression and to characterize confirmed p53 mutations in tumors from patients with clinically localized adenocarcinoma of the prostate. METHODS: p53 protein nuclear accumulation was determined immunohistochemically in the initial diagnostic tumor specimens from 37 patients with clinically localized prostate carcinoma. Two primary antibodies were used on all...

Topics

Adenocarcinoma
Aged
Base Sequence
DNA, Neoplasm
Genes, p53
Humans
Male
Molecular Sequence Data
Mutation
Prostatic Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 7879337
DOI: 10.1016/s0090-4295(99)80018-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7879337-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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