Article
Comparison of association methods for dense marker data.
Genetic epidemiology - 1 Dec 2008
Bacanu Silviu-Alin, Nelson Matthew R, Ehm Margaret G
Abstract excerpt
While data sets based on dense genome scans are becoming increasingly common, there are many theoretical questions that remain unanswered. How can a large number of markers in high linkage disequilibrium (LD) and rare disease variants be simulated efficiently? How should markers in high LD be analyzed: individually or jointly? Are there fast and simple methods to adjust for correlation of tests? What is the power...
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