Article
Testing for candidate gene linkage disequilibrium using a dense array of single nucleotide polymorphisms in case-parents studies.
Epidemiology (Cambridge, Mass.) - 1 Sept 2002
Lee Wen-Chung
Abstract excerpt
The future of genetic studies of complex human diseases will rely more and more on the epidemiologic association paradigm, in particular the use of the transmission/disequilibrium test to detect linkage disequilibrium in a case-parents study. With the rapid progress in genomic studies, many single nucleotide polymorphisms will be identified and genotyped within a very short physical distance. Analyzing multiple...
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