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Article

HAPGEN2: simulation of multiple disease SNPs.

Bioinformatics (Oxford, England) - 15 Aug 2011

Su Zhan, Marchini Jonathan, Donnelly Peter

Abstract excerpt

MOTIVATION: Performing experiments with simulated data is an inexpensive approach to evaluating competing experimental designs and analysis methods in genome-wide association studies. Simulation based on resampling known haplotypes is fast and efficient and can produce samples with patterns of linkage disequilibrium (LD), which mimic those in real data. However, the inability of current methods to simulate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21653516
DOI: 10.1093/bioinformatics/btr341
PMCID: PMC3150040

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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