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Article

Rapid simulation of P values for product methods and multiple-testing adjustment in association studies.

American journal of human genetics - 1 Mar 2005

Seaman S R, Müller-Myhsok B

Abstract excerpt

A major aim of association studies is the identification of polymorphisms (usually SNPs) associated with a trait. Tests of association may be based on individual SNPs or on sets of neighboring SNPs, by use of (for example) a product P value method or Hotelling's T test. Linkage disequilibrium, the nonindependence of SNPs in physical proximity, causes problems for all these tests. First, multiple-testing...

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Identifiers

PMID: 15645388
DOI: 10.1086/428140
PMCID: PMC1196392

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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