Article
Evaluation of genome-wide power of genetic association studies based on empirical data from the HapMap project.
Human molecular genetics - 15 Oct 2007
Nannya Yasuhito, Taura Kenjiro, Kurokawa Mineo, Chiba Shigeru, Ogawa Seishi
Abstract excerpt
With recent advances in high-throughput single nucleotide polymorphism (SNP) typing technologies, genome-wide association studies have become a realistic approach to identify the causative genes that are responsible for common diseases of complex genetic traits. In this strategy, a trade-off between the increased genome coverage and a chance of finding SNPs incidentally showing a large statistics becomes serious...
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