Article
Identification of the N-linked glycosylation sites of the human relaxin receptor and effect of glycosylation on receptor function.
Biochemistry - 1 Jul 2008
Yan Y, Scott D J, Wilkinson T N, Ji J, Tregear G W, Bathgate R A D
Abstract excerpt
The relaxin receptor, RXFP1, is a member of the leucine-rich repeat-containing G-protein-coupled receptor (LGR) family. These receptors are characterized by a large extracellular ectodomain containing leucine-rich repeats which contain the primary ligand binding site. RXFP1 contains six putative Asn-linked glycosylation sites in the ectodomain at positions Asn-14, Asn-105, Asn-242, Asn-250, Asn-303, and Asn-346,...
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