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Article

Probing the functional domains of relaxin-3 and the creation of a selective antagonist for RXFP3/GPCR135 over relaxin receptor RXFP1/LGR7.

Annals of the New York Academy of Sciences - 1 Apr 2009

Liu Changlu, Kuei Chester, Sutton Steven, Shelton Jonathan, Zhu Jessica, Nepomuceno Diane, Hossain Mohammed Akhter, Wade John D, Bathgate Ross A D, Bonaventure Pascal, Lovenberg Timothy

Abstract excerpt

Both relaxin-3 and its receptor (RXFP3, also known as GPCR135) are predominantly expressed in brain regions known to play important roles in processing sensory signals. Recent studies have shown that relaxin-3 is involved in the regulation of stress and feeding behaviors. The mechanisms underlying the involvement of relaxin-3/RXFP3 in the regulation of stress, feeding, and other potential functions remain to be...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19416155
DOI: 10.1111/j.1749-6632.2008.03790.x

Genes

RXFP3
RXFP1
INSL5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Probing the functional domains of relaxin-3 and the creation of a selective antagonist for RXFP3/GPCR135 over relaxin receptor RXFP1/LGR7.PMID 19416155Read ↗

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