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Article

Commonality of functional annotation: a method for prioritization of candidate genes from genome-wide linkage studies.

Nucleic acids research - 1 Mar 2008

Shriner Daniel, Baye Tesfaye M, Padilla Miguel A, Zhang Shiju, Vaughan Laura K, Loraine Ann E

Abstract excerpt

Linkage studies of complex traits frequently yield multiple linkage regions covering hundreds of genes. Testing each candidate gene from every region is prohibitively expensive and computational methods that simplify this process would benefit genetic research. We present a new method based on commonality of functional annotation (CFA) that aids dissection of complex traits for which multiple causal genes act in...

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Identifiers

PMID: 18263617
DOI: 10.1093/nar/gkn007
PMCID: PMC2275105

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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