Article

Discovering genetic interactions bridging pathways in genome-wide association studies

2017-08-30

Abstract excerpt

Genetic interactions have been reported to underlie phenotypes in a variety of systems, but the extent to which they contribute to complex disease in humans remains unclear. In principle, genome-wide association studies (GWAS) provide a platform for detecting genetic interactions, but existing methods for identifying them from GWAS data tend to focus on testing individual locus pairs, which undermines statistical...

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Literature Corpus work: 263aaeeb-5ebd-5df0-993b-06ef910f7886
DOI: 10.1101/182741

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