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Article

Testing groups of genomic locations for enrichment in disease loci using linkage scan data: a method for hypothesis testing.

Human genomics - 1 Jun 2006

Avramopoulos Dimitrios, Zandi Peter, Gherman Adrian, Fallin M Daniele, Bassett Susan S

Abstract excerpt

Genes for complex disorders have proven hard to find using linkage analysis. The results rarely reach the desired level of significance and researchers often have failed to replicate positive findings. There is, however, a wealth of information from other scientific approaches which enables the formation of hypotheses on groups of genes or genomic regions likely to be enriched in disease loci. Examples include...

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Identifiers

PMID: 16848972
DOI: 10.1186/1479-7364-2-6-345
PMCID: PMC3525155

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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