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Article

Detecting local genetic correlations with scan statistics.

Nature communications - 1 Apr 2021

Guo Hanmin, Li James J, Lu Qiongshi, Hou Lin

Abstract excerpt

Genetic correlation analysis has quickly gained popularity in the past few years and provided insights into the genetic etiology of numerous complex diseases. However, existing approaches oversimplify the shared genetic architecture between different phenotypes and cannot effectively identify precise genetic regions contributing to the genetic correlation. In this work, we introduce LOGODetect, a powerful and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33795679
DOI: 10.1038/s41467-021-22334-6
PMCID: PMC8016883

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