Article
Glucocorticoid receptor gene polymorphisms in premenopausal women with major depression.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme - 1 Mar 2008
Krishnamurthy P, Romagni P, Torvik S, Gold P W, Charney D S, Detera-Wadleigh S, Cizza G
Abstract excerpt
Glucocorticoid receptor gene polymorphisms are associated with glucocorticoid hypersensitivity and visceral obesity. Perturbations in HPA axis sensitivity to glucocorticoids implicated in the pathogenesis of major depression may result from functional alterations in the glucocorticoid receptor gene. We 1) examined the prevalence of genotype distribution of specific polymorphisms of the glucocorticoid receptor...
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