Article
Association between genetic variants and depression in a Romanian cohort.
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie - 1 Jan 2000
Costache Andrei, Riza Anca Lelia, Popescu Mihaela, Streaţă Ioana, Dincă Mihaela Eugenia, Glăvan Daniela Gabriela, Vladu Ionela Mihaela, Udriştoiu Ion, Ioana Mihai
Abstract excerpt
Major depressive disorder (MDD) is beyond doubt a common, disabling, and costly condition. MDD associates hypothalamic-pituitary-adrenal (HPA) axis alterations. We sought to investigate two candidate variants which could have a role in the genetic susceptibility for stress or corticoid-induced MDD: glucocorticoid receptor (GR) - nuclear receptor subfamily 3 group C member 1 (NR3C1) rs41423247 and brain-derived...
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