Article
Association of glucocorticoid and type 1 corticotropin-releasing hormone receptors gene variants and risk for depression during pregnancy and post-partum.
Journal of psychiatric research - 1 Sept 2013
Engineer Neelam, Darwin Lucy, Nishigandh Deole, Ngianga-Bakwin Kandala, Smith Steve C, Grammatopoulos Dimitris K
Abstract excerpt
Women with postnatal depression (PND) appear to have abnormal hypothalamic pituitary adrenal (HPA) axis responses to stress, which might involve a genetic variability component. We investigated association of genetic variants in the glucocorticoid receptor (GR, NR3C1) and corticotropin releasing hormone receptor 1 (CRHR1) genes with increased risk for PND. Two hundred pregnant women were recruited prospectively...
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