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Article

Common genetic polymorphisms in the ABCB1 gene are associated with risk of major depressive disorder in male Portuguese individuals.

Genetic testing and molecular biomarkers - 1 Jan 2014

Santos Marlene, Carvalho Serafim, Lima Luís, Nogueira Augusto, Assis Joana, Mota-Pereira Jorge, Pimentel Paulo, Maia Dulce, Correia Diana, Gomes Sofia, Cruz Agostinho, Medeiros Rui

Abstract excerpt

Major depressive disorder (MDD) is a highly prevalent disorder, which has been associated with an abnormal response of the hypothalamus-pituitary-adrenal (HPA) axis. Reports have argued that an abnormal HPA axis response can be due to an altered P-Glycoprotein (P-GP) function. This argument sugge...

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Source

Identifiers

PMID: 24200053
DOI: 10.1089/gtmb.2013.0197

Genes

ABCB1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24200053-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

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Common genetic polymorphisms in the ABCB1 gene are associated with risk of major depressive disorder in male Portuguese individuals.PMID 24200053Read ↗

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