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Article

Glucocorticoid Receptor Genetic Variants and Response to Fluoxetine in Major Depressive Disorder.

The Journal of neuropsychiatry and clinical neurosciences - 1 Jan 2018

Nouraei Hasti, Firouzabadi Negar, Mandegary Ali, Zomorrodian Kamiar, Bahramali Ehsan, Shayesteh Mohammad Reza Hooshangi, Ansari Saham

Abstract excerpt

Hyperactivity of the hypothalamic pituitary adrenocortical (HPA) axis is one of the main clinical findings in depression. The HPA axis is interrelated with glucocorticoid signaling via glucocorticoid receptors (GCRs). Thus, functional genetic variants on GCRs might influence therapeutic outcomes in depression. The aim of the present study was to investigate the association between three functional polymorphisms...

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Identifiers

PMID: 28641498
DOI: 10.1176/appi.neuropsych.16120322

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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