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Article

Glucocorticoid receptor polymorphism is associated with major depression and predominance of depression in the course of bipolar disorder.

Journal of affective disorders - 1 Nov 2011

Szczepankiewicz Aleksandra, Leszczyńska-Rodziewicz Anna, Pawlak Joanna, Rajewska-Rager Aleksandra, Dmitrzak-Weglarz Monika, Wilkosc Monika, Skibinska Maria, Hauser Joanna

Abstract excerpt

BACKGROUND: A strong association has been found between dysregulation of hypothalamic-pituitary-adrenal (HPA) axis and depression and bipolar disorder. Glucocorticoid receptor is one of the involved receptors and its gene has been recognized as a candidate gene for major depressive disorder and bipolar disorder. Therefore, we investigated if polymorphism of the glucocorticoid receptor gene (NR3C1), involved in...

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Source

Identifiers

PMID: 21764460
DOI: 10.1016/j.jad.2011.06.020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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