Article
Association of polymorphisms in one-carbon metabolizing genes and lung cancer risk: a case-control study in Chinese population.
Lung cancer (Amsterdam, Netherlands) - 1 Jul 2008
Liu Hongliang, Jin Guangfu, Wang Haifeng, Wu Wenting, Liu Yanhong, Qian Ji, Fan Weiwei, Ma Hongxia, Miao Ruifen, Hu Zhibin, Sun Weiwei, Wang Yi, Jin Li, Wei Qingyi, Shen Hongbing, Huang Wei, Lu Daru
Abstract excerpt
One-carbon metabolism facilitates the cross-talk between genetic and epigenetic processes, making it a good candidate for studying the risk of lung cancer. To investigate the role of common variants of one-carbon metabolizing genes on lung cancer risk, total 25 single nucleotide polymorphisms (SNPs) in 7 genes were genotyped among 500 incident lung cancer patients and 517 cancer-free controls. An increased risk...
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