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Article

One-carbon metabolism gene polymorphisms and risk of non-Hodgkin lymphoma in Australia.

Human genetics - 1 Dec 2007

Lee Kyoung-Mu, Lan Qing, Kricker Anne, Purdue Mark P, Grulich Andrew E, Vajdic Claire M, Turner Jennifer, Whitby Denise, Kang Daehee, Chanock Stephen, Rothman Nathaniel, Armstrong Bruce K

Abstract excerpt

Dysregulation of the one-carbon metabolic pathway, which controls nucleotide synthesis and DNA methylation, may promote lymphomagenesis. We evaluated the association between polymorphisms in one-carbon metabolism genes and risk of non-Hodgkin lymphoma (NHL) in a population-based case-control study in Australia. Cases (n = 561) and controls (n = 506) were genotyped for 14 selected single-nucleotide polymorphisms...

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Source

Identifiers

PMID: 17891500
DOI: 10.1007/s00439-007-0431-2

Genes

MTHFR
TYMS
CBS
FPGS
MTHFS
MTR
SHMT1
TCN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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