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1-CMDb: A Curated Database of Genomic Variations of the One-Carbon Metabolism Pathway.

Public health genomics - 1 Jan 2017

Bhat Manoj K, Gadekar Veerendra P, Jain Aditya, Paul Bobby, Rai Padmalatha S, Satyamoorthy Kapaettu

Abstract excerpt

BACKGROUND: The one-carbon metabolism pathway is vital in maintaining tissue homeostasis by driving the critical reactions of folate and methionine cycles. A myriad of genetic and epigenetic events mark the rate of reactions in a tissue-specific manner. Integration of these to predict and provide personalized health management requires robust computational tools that can process multiomics data. The DNA sequences...

Topics

Carbon
CpG Islands
DNA Copy Number Variations
Databases, Genetic
Genomics
Humans
MicroRNAs
Phenotype
Polymorphism, Single Nucleotide
Sequence Analysis, DNA

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PMID: 28511181
DOI: 10.1159/000475805

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