Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variants in one-carbon metabolism-related genes contribute to NSCLC prognosis in a Chinese population.

Cancer - 15 Dec 2010

Jin Guangfu, Huang Jinlin, Hu Zhibin, Dai Juncheng, Tang Rong, Chen Yijiang, Xu Lin, Huang Xinen, Shu Yongqian, Shen Hongbing

Abstract excerpt

BACKGROUND: One-carbon metabolism plays a critical role in DNA methylation and DNA synthesis. Variants of genes involved in one-carbon metabolism may result in aberrant methylation and/or DNA synthesis inhibition, and ultimately modulate the initiation and progression of tumors. In this study, the authors hypothesized that polymorphisms in one-carbon metabolism-related genes may contribute to the prognosis of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to Carcinoma, Non-Small-Cell Lung

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methylation

Share to Ferredoxin-NADP Reductase

Share to Lung Neoplasms

Share to Methylenetetrahydrofolate Dehydrogenase (NADP)

Share to Minor Histocompatibility Antigens

Share to Tetrahydrofolate Dehydrogenase

Source

Identifiers

PMID: 20737570
DOI: 10.1002/cncr.25301

Genes

DHFR
MTHFD1
MTR
MTRR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variants in one-carbon metabolism-related genes contribute to NSCLC prognosis in a Chinese population.PMID 20737570Read ↗

Genetic Variants in One-Carbon Metabolism Pathway Predict Survival Outcomes of Early-Stage Non-Small Cell Lung Cancer.Semantic proximity Read ↗

Association of polymorphisms in one-carbon metabolizing genes and lung cancer risk: a case-control study in Chinese population.Semantic proximity Read ↗

One-carbon metabolism pathway gene variants and risk of clear cell renal cell carcinoma in a Chinese population.Semantic proximity Read ↗

One-carbon metabolism gene polymorphisms and risk of non-Hodgkin lymphoma in Australia.Semantic proximity Read ↗

Genetic variations in the one-carbon metabolism pathway genes and susceptibility to hepatocellular carcinoma risk: a case-control study.Semantic proximity Read ↗

1-CMDb: A Curated Database of Genomic Variations of the One-Carbon Metabolism Pathway.Semantic proximity Read ↗

Single nucleotide polymorphisms of one-carbon metabolism and cancers of the esophagus, stomach, and liver in a Chinese population.Semantic proximity Read ↗

One-carbon genetic variants and the role of MTHFD1 1958G>A in liver and colon cancer risk according to global DNA methylation.Semantic proximity Read ↗

Genetic polymorphisms in the one-carbon metabolism pathway genes and susceptibility to non-Hodgkin lymphoma.Semantic proximity Read ↗

Comprehensive Analyses of One-carbon Metabolism Related Genes and Their Association with Prognosis, Tumor microenvironment, Chemotherapy Resistance and Immunotherapy in Lung AdenocarcinomaSemantic proximity Read ↗

Impact of one-carbon metabolism-related gene polymorphisms on risk of lung cancer in Japan: a case control study.Semantic proximity Read ↗

Functional variants of the 5-methyltetrahydrofolate-homocysteine methyltransferase gene significantly increase susceptibility to prostate cancer: Results from an ethnic Han Chinese population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.