Article
Genetic variations in the one-carbon metabolism pathway genes and susceptibility to hepatocellular carcinoma risk: a case-control study.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Feb 2015
Zhang Heng, Liu Chunhe, Han Yu-Chen, Ma Zuohong, Zhang Haiyan, Ma Yinan, Liu Xiaofang
Abstract excerpt
Hepatocellular carcinoma (HCC) is the sixth common cancer and the third common cause of cancer mortality worldwide. However, the exact molecular mechanism of HCC remains uncertain. Many enzymes are involved in one-carbon metabolism (OCM), and single nucleotide polymorphisms (SNPs) in the correspo...
Topics
- Adult
- Aged
- Alleles
- Asian People
- Carbon-Nitrogen Ligases
- Carcinoma, Hepatocellular
- Female
- Genetic Association Studies
- Genetic Predisposition to Disease
- Genotype
- Humans
- Liver Neoplasms
- Male
- Middle Aged
- One-Carbon Group Transferases