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Article

No support for a truncated interferon-alpha 17 allele as risk factor for MS.

European journal of neurology - 1 Nov 2007

Nyström M, Ruuth K, Lundgren E, Sundström P

Abstract excerpt

Cytokines have a central role in multiple sclerosis (MS) pathogenesis and may contribute to the aetiology of MS. A polymorphism in the IFNA17 gene with an allele carrying a pre-mature stop codon has been suggested to convey a 26-fold increased risk for MS. We investigated the possible association between this polymorphism and MS using population-based samples from a genetically well-characterized population. The...

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Source

Identifiers

PMID: 17956450
DOI: 10.1111/j.1468-1331.2007.01953.x

Genes

IFNA17

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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