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Article

IL28B polymorphisms are not associated with the response to interferon-β in multiple sclerosis.

Journal of neuroimmunology - 28 Oct 2011

Malhotra S, Morcillo-Suárez C, Brassat D, Goertsches R, Lechner-Scott J, Urcelay E, Fernández O, Drulovic J, García-Merino A, Martinelli Boneschi F, Chan A, Vandenbroeck K, Navarro A, Bustamante M F, Río J, Akkad D A, Giacalone G, Sánchez A J, Leyva L, Alvarez-Lafuente R, Zettl U K, Oksenberg J, Montalban X, Comabella M

Abstract excerpt

Recent studies have revealed an association between interleukin 28B (IL28B) and response to IFN-alpha treatment in hepatitis C patients. Here we investigated the influence of IL28B polymorphisms in the response to interferon-beta (IFNβ) in multiple sclerosis (MS) patients. We genotyped two SNPs of the IL28B gene (rs8099917 and rs12979860) in 588 MS patients classified into responders (n=281) and non-responders...

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Identifiers

PMID: 21889215
DOI: 10.1016/j.jneuroim.2011.08.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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