MS susceptibility is not affected by single nucleotide polymorphisms in the MMP9 gene.

doi:10.1016/j.jneuroim.2015.01.008

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Article

MS susceptibility is not affected by single nucleotide polymorphisms in the MMP9 gene.

Journal of neuroimmunology - 15 Feb 2015

Nischwitz S, Wolf C, Andlauer T F M, Czamara D, Zettl U K, Rieckmann P, Buck D, Ising M, Bettecken T, Mueller-Myhsok B, Weber F

Abstract excerpt

Matrix metalloproteinase 9 (MMP9) plays an important role in the pathogenesis of multiple sclerosis (MS). However, the impact of genetic variants affecting MMP9 on MS susceptibility is still in debate. We could not detect an association of MMP9 SNPs with MS on a genome-wide significance level by SNP genotyping, followed by imputation of SNPs within a region stretching 2Mbp up- and down-stream of MMP9. Rs6073751,...

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Identifiers

PMID: 25670000
DOI: 10.1016/j.jneuroim.2015.01.008

Genes

MMP9
WFDC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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