Functional variants of MIF, INFG and TFNA genes are not associated with disease susceptibility or hearing loss progression in patients with Ménière's disease.

doi:10.1007/s00405-012-2268-0

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Article

Functional variants of MIF, INFG and TFNA genes are not associated with disease susceptibility or hearing loss progression in patients with Ménière's disease.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery - 1 Mar 2013

Gázquez Irene, Moreno Antonia, Requena Teresa, Ohmen Jeff, Santos-Perez Sofia, Aran Ismael, Soto-Varela Andres, Pérez-Garrigues Herminio, López-Nevot Alicia, Batuecas Angel, Friedman Rick A, López-Nevot Miguel A, López-Escamez Jose A

Abstract excerpt

Variability in acute immune response genes could determine susceptibility or prognosis for Ménière's disease (MD). The cytokines tumor necrosis factor α (TNFα), macrophage migration inhibitory factor (MIF) and interferon γ (INFγ) are proinflammatory cytokines of the innate immune response. These cytokines mediate inflammation and have been previously associated with the inflammatory process in several autoimmune...

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Identifiers

PMID: 23179933
DOI: 10.1007/s00405-012-2268-0

Genes

MIF
IFNG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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