Article
IGHV4-39 deletion polymorphism does not associate with risk or outcome of multiple sclerosis.
Journal of neuroimmunology - 25 Aug 2010
Watson Corey T, Ramagopalan Sreeram V, Morrison Katie M, Ebers George C, Breden Felix
Abstract excerpt
The restricted use of immunoglobulin heavy chain variable (IGHV) family 4 gene segments by clonally expanded B cells in brain lesions and cerebrospinal fluid (CSF) of multiple sclerosis (MS) patients is well documented. Specifically, the overrepresentation of gene IGHV4-39 has been highlighted in...
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