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Article

T-1237C polymorphism of TLR9 gene is not associated with multiple sclerosis in the Portuguese population.

Multiple sclerosis (Houndmills, Basingstoke, England) - 1 May 2008

Carvalho A, Santos M, Maciel P, Rodrigues F

Abstract excerpt

Multiple sclerosis (MS) is an inflammatory disease of the central nervous system, with disturbances of the immunological balance. As TLR9-null mice showed increased resistance to experimental autoimmune encephalomyelitis and recent genetic investigations showed that T-1237C promoter polymorphism of TLR9, commonly implicated in autoimmune diseases, induces a deregulation of its expression, we performed an...

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Source

Identifiers

PMID: 18208876
DOI: 10.1177/1352458507084594

Genes

TLR9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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