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Article

No association of IFI16 (interferon-inducible protein 16) variants with susceptibility to multiple sclerosis.

Journal of neuroimmunology - 15 Jun 2014

Guerini Franca R, Clerici Mario, Cagliani Rachele, Malhotra Sunny, Montalban Xavier, Forni Diego, Agliardi Cristina, Riva Stefania, Caputo Domenico, Galimberti Daniela, Asselta Rosanna, Fenoglio Chiara, Scarpini Elio, Comi Giacomo P, Bresolin Nereo, Comabella Manuel, Sironi Manuela

Abstract excerpt

IFI16 encodes a nucleic acid-sensor which detects latent EBV and triggers inflammasome activation. We analysed IFI16 variants in two multiple sclerosis (MS) case-control cohorts from Italy and Spain; results were combined with a previous study. A risk variant for celiac disease/rheumatoid arthritis, a polymorphic exon 7 duplication, and a copy number variant (CNV) in the 5' region were genotyped. No significant...

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Source

Identifiers

PMID: 24794504
DOI: 10.1016/j.jneuroim.2014.04.006

Genes

IFI16

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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